Immunoglobulin isotype IgG1
Also known as Nkx3.1
Subcategory Mnoclonal antibodies
Source organism Human (Homo sapiens)
Host organism Mouse (Mus musculus)
Purification method Affinity Purified by Protein A chromatography
Form/Appearance Supplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
Other gene names NKX3-1; NKX3-1; NKX3; BAPX2; NKX3A; NKX3.1; NKX3.1; NKX3A
Gene name synonims NKX3-1; NKX3-1; NKX3; BAPX2; NKX3A; NKX3.1; NKX3.1; NKX3A
Gene name NKX3-1; NKX3-1; NKX3; BAPX2; NKX3A; NKX3.1; NKX3.1; NKX3A
Tested applications: ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC)
Species reactivity Human (Homo sapiens); Due to limited knowledge and inability for testing each and every species, the reactivity of the antibody may extend to other species which are not listed hereby.
Other names NK3 homeobox 1; Homeobox protein Nkx-3.1; homeobox protein Nkx-3.1; OTTHUMP00000123534; NK homeobox, family 3, A; homeobox protein NK-3 homolog A; NK3 transcription factor homolog A; NK3 transcription factor related, locus 1; NK3 homeobox 1; Homeobox protein NK-3 homolog A
Storage and shipping Store the antibody at +4 degrees Celsius for short term storage.. Aliquot to avoid repeated freezing and thawing. For optimal long term storage, the antibody should be kept at -20 degrees Celsius. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Specificity and cross-reactivity Recognizes human Nkx3.1 protein at ~34kD. Does not crossreact with mouse. Reactivity has been confirmed with human LN Cap-FGC prostate carcinoma cell lysates.; Since it is not possible to test each and every species our knowledge on the corss reactivity of the antibodies is limited. This particular antibody might cross react with speacies outside of the listed ones.
Description Aplha, transcription related growth factors and stimulating factors or repressing nuclear factors are complex subunits of proteins involved in cell differentiation. Complex subunit associated factors are involved in hybridoma growth, Eosinohils, eritroid proliferation and derived from promotor binding stimulating subunits on the DNA binding complex. NFKB 105 subunit for example is a polypetide gene enhancer of genes in B cells.The activation of transcription factor subunits is the first step of gene expression, in which a particular segment of DNA is copied into RNA (mRNA) by the enzyme RNA polymerases. Transcription factors, unites and elongations can be RNA and DNA nucleic acids, base pairs of nucleotides . Converting from DNA to RNA is made by enzymatic reactions. During transcription, a DNA sequence is read by an RNA polymerase, which produces a complementary, anti-parallel RNA strand called a primary transcript. Transcriptions are key functions in signal transduction pathways. Signaling ligand binding transcription factors play an important role in transduction cascades.